The 10 Best Dermatologist-Recommended Growth Factor Serums for Younger Skin

When it comes to anti-aging serums, there's no shortage of skin care products that can help give your complexion a radiant, youthful look. While it can be hard to figure out what's worth adding to your routine dermatologists say growth factor serums are worth the hype. It's a powerful, skin-friendly blend that's arguably one of the best all-in-one powerhouse products for healthy skin at any age. 

Marisa Garshick, MD, a leading board-certified dermatologist at Dermatology and Cosmetic Surgery in Manhattan, New York, explains that Growth Factor Serum is made up of proteins called growth factors that help repair the skin naturally. 

"Growth factors are produced naturally in the body, but levels decrease with age." These proteins play an important role in collagen production and skin regeneration, fighting issues like skin sagging, fine lines and wrinkles, as well as overall hydration and skin health. 

Karan Lal, D.O., M.S., F.A.A.D., a double board-certified dermatologist at Affiliated Dermatology in Scottsdale, Arizona, explains that there are many types of growth factors that can be human-derived, synthetic or natural (e.g., from plants) or snail). Candidates who are good at using human growth factors or growth factors synthesized based on human growth factors to produce maximum efficacy products will be given priority. 

The best thing about using growth factors is that they are often used in conjunction with other products, making serums an easy addition to your already established skin care routine. 

Experts even say that growth factor serums are less irritating than retinol and retinoids (which they still recommend if tolerated). Next, learn about the best growth factor serums recommended by dermatologists and all the benefits associated with powerful anti-aging products. 

1. SkinMedica TNS Advanced+ Serum: If you're looking for one of the best, most premium growth factor serums out there, look no further than this one from SkinMedica a favorite of Dr. Garshick says it "uses a blend of next-generation growth factors and an innovative peptide complex to nourish skin" while smoothing fine lines and wrinkles and improving skin tone and texture. 

2. INKEY List 15% Vitamin C+EGF Essence: This option from the Inkey List is both effective and affordable. PhD. Lal estimated that it contained oligopeptide-1, which he called a "true growth factor." 

This lightweight serum also contains vitamin C, making it a great option for those who want a smoother, firmer appearance and a brighter complexion. 

3. Perricone MD high-efficiency growth factor firming and lifting serum PhD. Lal recommends this growth factor serum because of its innovative formula that tones and conditions the skin. Not only does this serum contain growth factors, it also contains retinol for maximum skin-enhancing results. The benefits of retinol overlap with those of growth factors such as firming, tightening and brightening, as both ingredients support collagen production. However, the retinol in this formula also supports skin renewal and exfoliation. 

4. iS Clinical Youth Serum For those with more sensitive skin, the formula is enriched with centella asiatica, which "helps tighten the skin while soothing it," explains Dr. Garsik. "This serum provides immediate and long-term results to help firm, smooth and restore skin." 

5. ZO Skin Health Growth Factor Serum PhD. Lal says this serum from ZO Skin Health is a "really good product" because it helps reduce visible signs of aging, such as fine lines, loss of elasticity, and uneven skin tone and texture. While growth factors typically help keep skin hydrated, this lightweight gel formula goes a step further with ingredients like glycerin, red ginseng extract, and a proprietary blend that the brand claims "supports skin's natural replenishment of hyaluronic acid." . 

6. PCA SKIN Pro Max Age Update "This serum helps tone and tighten the appearance of skin while reducing the appearance of fine lines and wrinkles," explains Dr. Gashik. “It utilizes patent-pending micro-growth factor technology that allows for deeper penetration, resulting in increased collagen production and support.” 

7. Neocutis Bioserum "This topical serum contains growth factors and proprietary peptides to improve the overall appearance of fine lines and wrinkles while improving skin texture, overall firmness and elasticity, and increasing moisture," says Dr. Gashik. "It's safe to apply to the face, neck and décolletage once or twice a day, followed by a moisturizer."

8.Biopelle Firming Day Serum According to Dr. Garshick is suitable for all skin types. "This serum contains antioxidants like vitamin C, niacinamide, and hyaluronic acid to help brighten and hydrate skin." It also helps reduce signs of sun damage. "It also contains high levels of growth factors that help repair skin and reduce signs of aging." 

9. iS Clinical Youth Eye Complex iS Clinical’s Youthful Eye Complex is a perfect fit for Dr. Garshick recommends iS Clinical Youth Serum. This eye serum uses the same blend of growth factors to reduce the appearance of fine lines and wrinkles around the delicate eye area while hydrating and providing antioxidant protection. “This product really helped lighten my dark circles. I can really feel the difference after using this cream, my skin feels firmer and smoother,” wrote one Dermstore reviewer. “After using this cream, I no longer have many wrinkles on my eyelids. Best buttercream ever. " 

10. MASKĀD Anti-Aging Serum This serum combines growth factors with powerful peptides to fight the visible signs of aging like fine lines and wrinkles, loss of elasticity and dullness. Plus, you can be sure it contains Oligopeptide-1, which Dr. gets his seal of approval when it comes to growth factors. "This stuff is amazing! It absorbs almost immediately and does wonders for my fine lines," wrote one Amazon reviewer. “Really plump and smooth!”